GLASS LAB · Medical Aesthetics Evidence Index 303 cells · 19,226 papers · 5,969 top-tier evidence

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Volume / Contour

See the procedure group × indication combinations in this category, ranked by evidence score. Grade reflects the volume and quality of research; direction reflects what the papers conclude.

GradeScoreDirectionIndicationProcedure groupRCT & metaClinical & observationalCase reportsTotal papers
A 95.4 Supported Nasolabial fold HA filler crosslinked 99 29 32 262
A 94.9 Supported Midface volume loss HA filler crosslinked 31 14 14 171
A 94.9 Supported Chin augmentation HA filler crosslinked 15 7 26 76
A 94.7 Supported Lip augmentation HA filler crosslinked 34 22 60 234
A 94.7 Supported Tear trough / infraorbital hollow HA filler crosslinked 14 11 35 135
A 94.6 Supported Lateral cheek volume HA filler crosslinked 10 12 20 125
A 94.6 Supported Jawline contour definition HA filler crosslinked 12 3 6 77
A 94.5 Supported Jawline contour definition CaHA filler 6 3 2 28
A 94.4 Supported Midface volume loss PLLA filler (Sculptra) 5 3 1 25
A 94.3 Supported Nasolabial fold CaHA filler 9 3 5 22
A 94.2 Supported Hand dorsum volume loss HA filler crosslinked 12 12 8 62
A 94.2 Supported Perioral lipstick lines HA filler crosslinked 6 1 0 11
A 93.3 Supported Hand dorsum volume loss CaHA filler 3 7 0 25
B 74.6 Supported Temporal hollow HA filler crosslinked 8 7 15 79
B 74.0 Supported Temporal hollow PLLA filler (Sculptra) 3 0 2 13
B 73.8 Supported Buttock contour PLLA filler (Sculptra) 2 0 3 12
B 73.0 Supported Prejowl sulcus HA filler crosslinked 1 0 1 11
C 54.2 Supported Marionette line HA filler crosslinked 2 1 0 20
C 53.7 Supported Midface volume loss Collagen stimulator PDLLA PLLA 1 0 0 4
D 34.6 Forehead volume / brow HA filler crosslinked 17 14 44 183
D 34.5 Insufficient Temporal hollow Collagen stimulator PDLLA PLLA 1 0 0 1
D 34.1 Insufficient Hand dorsum volume loss Adipose matrix (Renuva) 1 0 1 2
D 33.7 Chin augmentation CaHA filler 0 1 0 8
D 33.2 Buttock contour CaHA filler 1 1 0 7
D 33.2 Nasolabial fold Pdo PCL PLLA thread lifting 0 2 4 15
D 32.8 Ear lobe volume HA filler crosslinked 0 0 0 6
D 32.7 Insufficient Nasolabial fold PCL filler 0 0 0 1
D 32.1 Insufficient Hand dorsum volume loss PLLA filler (Sculptra) 0 3 1 14
D 32.0 Insufficient Neck horizontal lines CaHA filler 0 0 2 1
D 32.0 Insufficient Neck horizontal lines Collagen stimulator PDLLA PLLA 0 0 0 1
D 31.1 Insufficient Body localized volume defect Adipose matrix (Renuva) 0 0 0 2
F 12.0 Insufficient Lateral cheek volume Collagen stimulator PDLLA PLLA 0 0 0 6
F 10.0 Insufficient Neck horizontal lines Acellular dermal matrix ECM skinbooster 0 0 0 0
F 10.0 Insufficient Neck horizontal lines HA glycerol skinbooster 0 0 0 0
F 10.0 Insufficient Hand dorsum volume loss HA skin booster 0 0 0 0
F 10.0 Insufficient Neck horizontal lines HA skin booster 0 0 0 0
F 10.0 Insufficient Midface volume loss Hybrid dual HA skinbooster volume 0 0 0 0
F 10.0 Insufficient Neck horizontal lines Microdosed botulinum for skin 0 0 0 0
F 10.0 Insufficient Jawline contour definition PCL filler 0 0 0 0
F 10.0 Insufficient Marionette line PCL filler 0 0 0 0
F 10.0 Insufficient Midface volume loss PCL filler 0 0 0 0
F 10.0 Insufficient Neck horizontal lines PLLA filler (Sculptra) 0 0 0 0
F 10.0 Insufficient Neck horizontal lines PN PDRN injection with HA 0 0 0 0