CaHA filler evidence for Hand dorsum volume loss

Abstract summary (English) BACKGROUND: Calcium hydroxylapatite (CaHA) is currently the only FDA-approved soft-tissue filler indicated for augmentation of the dorsal hand. Although the treatment is generally safe and effective, adverse side effects such as swelling and edema postinjection are common and can sometimes be debilitating. OBJECTIVE: In this study, the authors explore the utility of triamcinolone acetate coinjection with CaHA to the...

Journal Article, Randomized Controlled Trial

Abstract summary (English) BACKGROUND: Calcium hydroxylapatite (CaHA) microspheres suspended in a carrier gel is an opaque dermal filler that has been used to provide immediate volume correction in the dorsal hands. OBJECTIVE: To assess the safety and effectiveness of CaHA for the correction of volume loss in the hands up to 12 months. MATERIALS AND METHODS: This multicenter, controlled, single-blind study (NCT01832090) included 114 subjects...

Journal Article, Multicenter Study, Randomized Controlled Trial

Abstract summary (English) BACKGROUND: Measurement scales that quickly and rigorously evaluate the effectiveness of filler treatment in hands are important tools in clinical practice. The Merz Hand Grading Scale (MHGS) is used to grade the appearance of the dorsal hand. The MHGS has been validated for photographic and live assessment of the hands.

Journal Article, Multicenter Study, Randomized Controlled Trial, Research Support, Non-U.S. Gov't

Abstract summary (English) There has been an increasing demand for hand rejuvenation procedures. Hand evaluation is critical before any such procedure, and recently proposed five-point scales, including the Merz Hand Grading Scale and Allergan Hand Volume Deficit Scale, provide an objective assessment of volume loss of soft tissues. Dermal fillers, including hyaluronic acid (HA), calcium hydroxylapatite (CaHA), and poly-L-lactic acid, can...

Journal Article, Review, Comparative Study

Abstract summary (English) BACKGROUND: Calcium hydroxylapatite (CaHA) is effective for dorsal hand rejuvenation. Higher dilutions are used for biostimulation with fewer side effects. OBJECTIVE: To evaluate the efficacy and safety of 2 techniques of diluted CaHA injection for dorsal hand treatment.

Clinical Trial, Comparative Study, Journal Article

Abstract summary (English) BACKGROUND: Volume restoration using filler in the dorsum of the hand is a simple and effective procedure to improve wrinkles and hide veins and tendons. Currently, calcium-hydroxyapatite (CaHA) filler is the only FDA-accepted material to use in the hand dorsum. However, it is not easy to inject due to swelling and redness.

Comparative Study, Journal Article, Video-Audio Media

Abstract summary (English) BACKGROUND: To retrospectively evaluate the rate of adverse events after hand volumizing procedures using a calcium hydroxylapatite product and to investigate the relationship between injector used (i.e., needle versus cannula) and technique applied (i.e., bolus, tenting, proximal-to-distal fanning, distal-to-proximal single line). METHODS: Two hundred twenty individuals, including 214 women (97.3 percent) aged 52.3...

Comparative Study, Journal Article

Abstract summary (English) BACKGROUND: Calcium hydroxylapatite filler (CaHA; Radiesse) is a synthetic, non-animal derived product composed of minerals that occur naturally in bone and teeth. Following its development in the US, initial approval by the US FDA for non-aesthetic indications and CE marking in Europe, it was used off FDA-labeling for aesthetic purposes. Its use has grown further since its FDA approval in 2006 for long-lasting...

Comparative Study, Journal Article, Review

Abstract summary (English) OBJECTIVES: the investigator sought to determine whether calcium hydroxylapatite (CaHA) could be used as dermal filler for replacement of volume loss in aging hands. METHODS: the principal investigator injected 1.3 mL of CaHA into the dorsal side of both hands (BH) of 10 female patients (57-68 years of age), for full correction. Investigator, independent evaluator and subjects assessed results at four time points.

Comparative Study, Journal Article

Abstract summary (English) BACKGROUND: Facial rejuvenation has traditionally centered on the correction of ptosis, lines, and wrinkles, typically achieved by surgical tightening of the skin or by injecting soft-tissue fillers. In recent years, volumetric augmentation and recontouring have been recognized as fundamentally important aspects of facial rejuvenation. METHODS: An overview of volume restoration and recontouring is presented.

Evaluation Study, Journal Article, Research Support, Non-U.S. Gov't