HA filler crosslinked evidence for Lateral cheek volume

Abstract summary (English) Skin aging causes cumulative structural, physiological, and progressive skin changes, as well as wrinkles, uneven skin tone, elasticity loss, and skin thinning. We performed a systematic review of nine studies involving 278 participants to assess the efficacy and safety of the stable, hybrid cooperative complexes of high molecular weight hyaluronic acid (HCC-HA) and low molecular weight hyaluronic acid used in...

Journal Article, Systematic Review, Review

Abstract summary (English) BACKGROUND: Various rejuvenation surgeries, including hyaluronic acid (HA) fillers, aim to address mid-face volume loss. However, literature on the comparative efficacy and safety of different HA fillers for the zygomatic area remains limited. METHODS: This systematic review and network meta-analysis (NMA), adhering to NMA PRISMA 2020 and Cochrane guidelines.

Systematic Review, Journal Article, Network Meta-Analysis

Abstract summary (English) BACKGROUND: Jowling is a common aesthetic complaint in aging individuals. OBJECTIVE: Injectable filler placed at the lateral jawline will improve the appearance of jowls, as defined by the Merz Aesthetic Jawline Grading Scale (MAJGS). This improvement will be independent of concomitant injection of filler into the lateral cheek.

Journal Article, Comparative Study, Randomized Controlled Trial

Abstract summary (English) BACKGROUND: With aging, there is a decrease in the volume of facial fat compartments, which can be restored using injectable biodegradable fillers. AIMS: The objective of this study was to assess the efficacy and safety of an ultrasound-guided transoral injection versus the traditional percutaneous approach for cheek volumization with hyaluronic acid. PATIENTS/METHODS: This is a pilot, single-center, comparative,...

Journal Article, Randomized Controlled Trial

Abstract summary (English) Injectable fillers represent one of the most requested minimally invasive treatments to rejuvenate the aging face, and its popularity is steadily rising. A vast majority of filler treatments are with hyaluronic acid (HA). The aim of this systematic review is to evaluate patient outcomes, safety profile, and administration techniques of various HA fillers for malar augmentation.

Journal Article, Systematic Review

Abstract summary (English) There has been an increasing role in the use of injectable fillers for rejuvenation of the aging face. In this systematic review, we aim to evaluate the existing literature related to soft tissue fillers of the midface. Specifically, we focus on the non-hyaluronic acid fillers including polymethylmethacrylate (PMMA), poly-L-lactic acid (PLLA), calcium hydroxyapatite (CaHA), and autologous fat.

Journal Article, Systematic Review

Abstract summary (English) Various hyaluronic acid fillers can be used for facial attenuation and rejuvenation. The efficacy and durability of hyaluronic acid fillers are of major concern to dermatologists and patients. This study aimed to evaluate three-dimensional morphology, tissue distribution, and changes in volume after injection of two different hyaluronic acid fillers.

Journal Article, Randomized Controlled Trial

Abstract summary (English) BACKGROUND: Hyaluronic acid gels are used to restore volume to the midface, but there are few data published on this use in Asian subjects. METHODS: This study evaluated the safety and effectiveness in Chinese subjects of Juvéderm Voluma, a 20-mg/ml hyaluronic acid gel formulated for midface volumizing. This prospective, multicenter study randomized 119 subjects aged 18 years or older to a treatment group and 27...

Comparative Study, Journal Article, Multicenter Study, Randomized Controlled Trial

Abstract summary (English) UNLABELLED:

BACKGROUND: Injection of hyaluronic acid (HA) volumizing fillers in the malar area is intended for rejuvenation of the mid-face. The choice of products, depth, and technique of injection depends on the desired level of volume enhancement and practitioners' preferences.

OBJECTIVE: To describe a volumizing injection technique in the scope of a controlled, randomized, double-blind, single-center,...

Journal Article, Randomized Controlled Trial

Abstract summary (English) BACKGROUND: Hyaluronic acid (HA) fillers are FDA approved for improving the appearance of the nasolabial folds. Previous reports on the use of HA for this treatment have focused on injections directly into the location of the desired correction. To our knowledge, a study has not been done evaluating the efficacy of injecting a low volume of HA into the adjacent area of volume loss to correct both volume loss and...

Comparative Study, Journal Article, Randomized Controlled Trial