Volume / Contour · Buttock contour
PLLA filler (Sculptra) evidence for Buttock contour
This is an early evidence stage based mainly on observational studies and case reports. Use it as supplementary reference, and follow your doctor's judgment for treatment decisions.
Grade combines the quantity and quality of the research, while direction is a separate signal showing how the papers assess effectiveness.
Median year 2022 Last 5 years 67% Positive results 67%
Known in Korea as
Procedure and brand names vary, but the evidence above applies to the same procedure mechanism.
Key papers
tier1 SPLASH: Split-Body Randomized Clinical Trial of Poly- l -Lactic Acid for Adipogenesis and Volumization of the Hip Dell.
Abstract summary (English) BACKGROUND: Injectable poly- l -lactic acid (PLLA-SCA) increases extracellular matrix to improve skin quality. The hip dell is an underappreciated element of gluteal aesthetics. Adipose tissue has roles in aesthetics and skin functioning.
Journal Article, Randomized Controlled Trial
View on PubMedtier1 A Randomized, Single-Center, Double-Blinded, Split-Body Clinical Trial of Poly- l -Lactic Acid for the Treatment of Cellulite of the Buttocks and Thighs.
Abstract summary (English) BACKGROUND: More than 90% of women report concerns of cellulite on their skin. Poly- l lactic acid (PLLA-SCA) is a biocompatible, semipermanent, synthetic filler that induces neocollagenesis. OBJECTIVE: To investigate the safety and efficacy of PLLA-SCA for the treatment of cellulite of the buttock and thigh regions.
Randomized Controlled Trial, Journal Article
View on PubMedtier0_review Safety and Efficiency of Minimally Invasive Buttock Augmentation: A Review.
Abstract summary (English) BACKGROUND: Volume restoration and enhancement of the gluteal region appearance has become nowadays a popular concern in particular for many women. Several options are available, none however are without complications and side effects. Volume enhancement with soft tissue fillers of the gluteal region is emerging as a highly attractive minimally invasive modality.
Journal Article, Review
View on PubMedtier0_review Poly-L-Lactic Acid for Gluteal Augmentation found to be Safe and Effective in Retrospective Clinical Review of 60 Patients.
Abstract summary (English) BACKGROUND: Poly-L-lactic acid (PLLA) is a well-established biostimulator that induces neocollagenesis, allowing for volume loss correction. Although PLLA is FDA approved to treat mid-to-lower facial wrinkling, it has grown increasingly popular as a nonsurgical, minimally invasive procedure for soft-tissue volume augmentation of other extremities. However, research detailing PLLA buttock injections is still lacking.
Journal Article, Review
View on PubMedtier0_review Poly-L-Lactic Acid for Minimally Invasive Gluteal Augmentation.
Abstract summary (English) BACKGROUND: There is increased emphasis on the importance of the gluteal region in the perception of beauty. Biodegradable fillers provide a nonsurgical method of augmenting and rejuvenating this area. OBJECTIVE: To review pertinent aspects of anatomy, patient evaluation, injection technique, and complications for gluteal augmentation using injectable biodegradable fillers.
Journal Article, Review
View on PubMedtier_other Multicentric Retrospective Study on Safety and Efficacy of a Novel Injectable Poly-l-Lactic Acid for Buttocks Recontouring.
Abstract summary (English) BACKGROUND: Poly-l-lactic acid (PLLA) injectables have gained increasing attention in aesthetic medicine due to their biocompatibility and long-lasting effects. Although their primary application centers around facial rejuvenation, their potential for off-label use in other body areas has been investigated, demonstrating promising outcomes in terms of both efficacy and safety. AIM: This study aims to assess the...
Journal Article, Multicenter Study
View on PubMedtier_other Targeted and Individualized Gluteal Poly-L-Lactic Acid Injection for Optimal Aesthetic Results in the Gluteal Region.
Abstract summary (English) OBJECTIVE: The robust safety and efficacy profile associated with the use of biodegradable fillers such as poly-L-lactic acid (PLLA) for facial rejuvenation has resulted in a growing interest in off-label use for various aesthetic applications, including gluteal augmentation. The authors describe a novel targeted and individualized technique of PLLA injection into the buttock region. METHODS: The technique involves...
Journal Article
View on PubMedtier_other Dynamic ultrasound evaluation of body fillers and biostimulators in the buttocks of fresh-frozen specimen.
Abstract summary (English) BACKGROUND: Ultrasound imaging is a useful tool to study the injection of fillers and biostimulators in the body. OBJECTIVE: Sonographically evaluate real-time injections of fillers and biostimulators and describe their behavior in the subcutaneous tissue of the buttocks of fresh-frozen specimen. METHODS: injection of two brands of high-density hyaluronic acid (HA), one brand of calcium hydroxyapatite (CaHA), one...
Journal Article
View on PubMedtier_other A Prospective, Multicenter Trial on the Efficacy and Safety of Poly-L-Lactic Acid for the Treatment of Contour Deformities of the Buttock Regions.
Abstract summary (English) BACKGROUND: There is a significant emphasis on minimally invasive whole-body rejuvenation throughout the world. Recently, gluteal aesthetics have become an increasingly common patient concern. Although the application of poly-L-lactic acid (PLLA) to the face is already well known, there are relatively fewer publications on its use in other corporeal regions.
Journal Article, Multicenter Study
View on PubMedtier_other Expert Recommendations on the Use of Injectable Poly-L-lactic Acid for Contour Deficiencies of the Buttocks.
Abstract summary (English) Poly-L-lactic acid (PLLA) is an injectable biodegradable biostimulator that promotes collagen production and is approved for use in aesthetic facial augmentation. PLLA is well tolerated with minimal downtime and has demonstrated an excellent safety profile, as well as a longevity benefit of at least 2 years following injection. The robust safety and efficacy profile associated with PLLA for facial rejuvenation has...
Journal Article
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