HA filler crosslinked evidence for Forehead volume / brow

Abstract summary (English) INTRODUCTION: Patients with systemic sclerosis (SSc) or morphea increasingly inquire about cosmetic procedures, as these conditions often result in disfiguring cutaneous manifestations such as microstomia, thin lips, sclerotic plaques or skin atrophy. Traditionally, rheumatologists prioritize immunosuppression and disease control but often fail to address aesthetic concerns. Among available interventions, hyaluronic...

Journal Article, Systematic Review, Review

Abstract summary (English) BACKGROUND AND AIM: With age, temple depressions appear due to age-related atrophy of fatty tissue, leading to a prominent cheekbone and lateral rim of the eye socket. Hyaluronic acid fillers have become very popular in the temple area due to their simple procedure and reliable results. The present study was conducted with the aim of determining the effectiveness of filler injection between the superficial and deep...

Journal Article, Meta-Analysis, Systematic Review

Abstract summary (English) BACKGROUND: As the popularity of non-hyaluronic acid (HA) injectables such as biostimulators rise in medical aesthetics, so have the rates of complications related to these injectables, including that of iatrogenic visual loss from vascular occlusion. METHODS: The authors conducted a systematic review of the available literature on visual loss related to the most widely used biostimulator injectables including...

Journal Article, Systematic Review, Review

Abstract summary (English) BACKGROUND: Temple hollowing is characterized by a reduction of volume in the temporal fossa, which can result in a skeletonized look and contribute to an aged appearance. This study aimed to evaluate the safety and effectiveness of VYC-20L injectable gel to improve temple hollowing. METHODS: Adults with minimal, moderate, or severe temple hollows were randomized 2:1 to receive VYC-20L or no treatment.

Journal Article, Randomized Controlled Trial, Multicenter Study

Abstract summary (English) BACKGROUND: The function of injectable hyaluronic acid-based fillers is to smooth dermal wrinkles formed during aging. The aim of this study is to evaluate the performance and safety of a dermal filler after its commercialization. METHODS: In this context, an 18-month prospective randomized single-blind study for the efficacy and safety of ART FILLER Fine Lines (AFFL) was performed on the forehead, the upper lip,...

Journal Article, Randomized Controlled Trial

Abstract summary (English) OBJECTIVE: The current study aims to investigate the safety and efficacy of using calcium hydroxyapatite (CaHA) versus CaHA associated with hyaluronic acid (HA) for forehead volume replacement and contour restoration without forehead irregularities. METHODS: This interventional study involved 132 participants in a two-arm, parallel, double-blind trial for forehead treatment using the supraperiosteal technique. Group...

Journal Article, Randomized Controlled Trial

Abstract summary (English) BACKGROUND: Adverse reactions, caused during the inflammation and healing process, or even later, can be induced by the injection of dermal filler and can present a variety of clinical and histological characteristics. In this study we aimed to review the adverse reactions associated with the injection of aesthetic filling materials in the face and neck. MATERIAL AND METHODS: The review was reported according to the...

Systematic Review, Journal Article

Abstract summary (English) BACKGROUND: With the global increase in the use of injectable fillers, more cases with serious adverse events such vision loss are being reported. This article aims to review the cases of hyaluronic acid (HA) filler-related vision loss and to discuss the potential efficacy of hyaluronidase (HYASE) treatment via different given methods. METHODS: A total of 29 articles presenting 144 cases of HA filler-related vision...

Journal Article, Systematic Review

Abstract summary (English) BACKGROUND: Botulinum toxin type A (BontA) is the most frequent treatment for facial wrinkles, but its effectiveness and safety have not previously been assessed in a Cochrane Review. OBJECTIVES: To assess the effects of all commercially available botulinum toxin type A products for the treatment of any type of facial wrinkles. SEARCH METHODS: We searched the following databases up to May 2020: the Cochrane Skin...

Journal Article, Meta-Analysis, Research Support, Non-U.S. Gov't, Systematic Review

Abstract summary (English) BACKGROUND: With the global increase in the use of injectable fillers, more cases with serious adverse events such as skin ischemia and vision loss are being reported. This article aims to review the role of HA fillers, as a subgroup separate from fat graft and non-HA fillers, in causing vision loss and to elucidate various features and outcomes of post-HA filler vision loss. METHODS: The preferred reporting items...

Journal Article, Systematic Review