HA filler crosslinked evidence for Lip augmentation

Abstract summary (English) Despite the growing demand for hyaluronic acid (HA) lip fillers, there is a paucity of robust, quantitative data across high-powered studies. This systematic review and meta-analysis aims to assess the efficacy and safety of HA lip fillers as reported by randomized controlled trials (RCTs). A systematic review was performed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-analyses...

Journal Article, Systematic Review, Meta-Analysis

Abstract summary (English) Lip augmentation procedures are increasingly popular in aesthetic medicine, and precise knowledge of labial arterial anatomy is essential for safe outcomes. The superior labial artery (SLA) and inferior labial artery (ILA) serve as critical anatomical landmarks for these procedures, and their positioning guides injection techniques. But despite their importance, there has been uncertainty about the precise depths of...

Journal Article, Meta-Analysis

Abstract summary (English) BACKGROUND: Lips are prone to dehydration and aging. Effective noninvasive hyaluronic acid (HA) delivery remains challenging. AIM: To evaluate topical Replenishing Lip Filler-Tiered Release Vesicles (RLF-TRV) in filler-naïve and previously-augmented lips.

Journal Article, Randomized Controlled Trial

Abstract summary (English) BACKGROUND: Lip augmentation using dermal fillers is increasingly popular, but often requires large volumes and regular touch-ups, whereas poor techniques and product selection can result in unnatural-looking lips. The RHA collection was designed to have less rigidity, allowing the products to adapt to facial animation. In particular, RHA3 has been approved in Europe for lip volumization.

Journal Article, Multicenter Study, Randomized Controlled Trial, Comparative Study, Equivalence Trial

Abstract summary (English) BACKGROUND: The function of injectable hyaluronic acid-based fillers is to smooth dermal wrinkles formed during aging. The aim of this study is to evaluate the performance and safety of a dermal filler after its commercialization. METHODS: In this context, an 18-month prospective randomized single-blind study for the efficacy and safety of ART FILLER Fine Lines (AFFL) was performed on the forehead, the upper lip,...

Journal Article, Randomized Controlled Trial

Abstract summary (English) BACKGROUND: Versatility, biocompatibility, and reversibility make hyaluronic acid fillers the backbone of minimally invasive lip augmentation procedures. OBJECTIVES: The aim of this study was to assess the effectiveness and short- and long-term safety of Saypha LIPS Lidocaine (Croma Pharma, Leobendorf, Austria) for lip augmentation to correct moderate to severe lip volume deficiency (grade 1-3 lip fullness score...

Journal Article, Multicenter Study, Randomized Controlled Trial

Abstract summary (English) The aim of this study was to systematically review the clinicopathological data regarding foreign body reactions (FBR) related to esthetic procedures in the orofacial region. Electronic searches were performed in six databases and in gray literature using PEO acronym for the review question. Case series and case reports describing FBR related to esthetic procedures in the orofacial region were included.

Journal Article, Systematic Review, Research Support, Non-U.S. Gov't

Abstract summary (English) BACKGROUND: The increased demand for minimally invasive facial cosmetic procedures in tandem with the ease of acquiring injectable cosmetics through direct-to-consumer retailers has led to a rise in self-injecting cosmetics among untrained individuals. OBJECTIVE: To analyze complications, treatments, and outcomes associated with self-injecting fillers into the face. METHODS: A systematic review of the literature...

Systematic Review, Journal Article

Abstract summary (English) OBJECTIVE: There is an abundance of information on facelifts, blepharoplasties, rhinoplasty, and other cosmetic surgical procedures for the upper third of the face, but little is known about perioral lip rejuvenation. The aim of this article is to examine the existing literature on lip rejuvenation and perioral procedures related to lip rejuvenation. Additionally, this article aims to highlight the importance of...

Systematic Review, Journal Article, Research Support, Non-U.S. Gov't

Abstract summary (English) BACKGROUND: Transient swelling is common after lip injections with hyaluronic acid (HA) based fillers. Swelling and other injection-site reactions may relate to the injection procedure itself, or to gel properties, which differ between fillers due to differences in manufacturing methods. OBJECTIVES: To evaluate safety and effectiveness of lip injections with two HA fillers manufactured using different gel...

Journal Article, Randomized Controlled Trial