GLASS LAB · Medical Aesthetics Evidence Index 303 cells · 19,226 papers · 5,969 top-tier evidence

Volume / Contour · Hand dorsum volume loss

PLLA filler (Sculptra) evidence for Hand dorsum volume loss

D 26.2 / 100 Insufficient 0 RCT/meta · 3 clinical/observational · 1 case · 14 total
Insufficient evidence

There is not yet enough PubMed evidence for this combination. The procedure exists, but research on this indication may be scarce.

Grade combines the quantity and quality of the research, while direction is a separate signal showing how the papers assess effectiveness.

Median year 2025 Last 5 years 50% Positive results 50%

Known in Korea as

스컬트라

Procedure and brand names vary, but the evidence above applies to the same procedure mechanism.

Key papers

tier2 Hand rejuvenation with dermal fillers: Key aspects and a comparison of commonly used fillers. Clinics in dermatology · 2025 · PMID 41365422

Abstract summary (English) There has been an increasing demand for hand rejuvenation procedures. Hand evaluation is critical before any such procedure, and recently proposed five-point scales, including the Merz Hand Grading Scale and Allergan Hand Volume Deficit Scale, provide an objective assessment of volume loss of soft tissues. Dermal fillers, including hyaluronic acid (HA), calcium hydroxylapatite (CaHA), and poly-L-lactic acid, can...

Journal Article, Review, Comparative Study

View on PubMed
tier_other High-Resolution Ultrasound Evaluation of Common Dorsal Hand Rejuvenation Techniques: A Multicenter Study. Cureus · 2026 · PMID 41658731

Abstract summary (English) Background Hand dorsum volumization is an increasingly used aesthetic procedure, but the ultrasonographic appearance of commonly injected materials has not been systematically described. High-resolution ultrasound with Doppler (HRUD) may provide an objective method to verify product placement and support safer, standardized hand rejuvenation. This descriptive study aimed to characterize the postprocedural...

Journal Article

View on PubMed
tier_other Clinical experience with complications of hand rejuvenation. Journal of plastic, reconstructive & aesthetic surgery : JPRAS · 2012 · PMID 22763320

Abstract summary (English) PURPOSE: Prominent signs of ageing of the hands have recently been treated with permanent or longer-lasting injectable dermal fillers. However, few previous studies have described the long-term complications of such hand rejuvenation. The purpose of our report was to share our experience of 15 cases with long-term complications following hand rejuvenation using various medical fillers.

Journal Article

View on PubMed
tier_other Treatment of the ageing hand with dermal fillers. Journal of cutaneous and aesthetic surgery · 2012 · PMID 23112510

Abstract summary (English) Following the trend in facial cosmetic procedures, patients are now increasingly requesting hand rejuvenation treatments. Intrinsic ageing of the hands is characterized by loss of dermal elasticity and atrophy of the subcutaneous tissue. Thus, veins, tendons and bony structures become apparent.

Journal Article

View on PubMed

Suggested interpretation

For reference

Personalized evidence report

Tell us more about your concern
and the Glass Lab bot will build a personalized report for you.

Based on the PLLA filler (Sculptra) · Hand dorsum volume loss information on this page, we'll email you an evidence summary tailored to your skin condition and treatment stage.

Concerns of interest (select multiple)
Decision stage
← Other indications for the same procedure group  |  Other procedures for the same indication →