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Compare the procedure groups used for this indication, ranked by evidence grade. Each grade comes from an expert read of the actual studies (design, quality, on-topic relevance); direction reflects what those studies conclude.
| Grade | Direction | Procedure group | RCT & meta | Clinical & observational | Case reports | Total papers |
|---|---|---|---|---|---|---|
| D | Insufficient | CaHA filler | 0 | 0 | 2 | 1 |
| D | Insufficient | Collagen stimulator PDLLA PLLA | 0 | 0 | 0 | 1 |
| F | Insufficient | Acellular dermal matrix ECM skinbooster | 0 | 0 | 0 | 0 |
| F | Insufficient | HA glycerol skinbooster | 0 | 0 | 0 | 0 |
| F | Insufficient | HA skin booster | 0 | 0 | 0 | 0 |
| F | Insufficient | Microdosed botulinum for skin | 0 | 0 | 0 | 0 |
| F | Insufficient | PLLA filler (Sculptra) | 0 | 0 | 0 | 0 |
| F | Insufficient | PN PDRN injection with HA | 0 | 0 | 0 | 0 |