What is the evidence for Adipose matrix (Renuva) treating Hand dorsum volume loss?

Confidence grade B (51 / 100). PubMed has 1 tier-1 papers (RCT, meta-analysis, systematic review), 0 tier-2 (clinical trial, observational), 1 tier-3 (case). Direction: insufficient.

What does the literature conclude about Adipose matrix (Renuva) for Hand dorsum volume loss?

Fewer than 3 papers state a clear outcome direction. Insufficient data to draw a conclusion.

Volume / Contour · Hand dorsum volume loss

Adipose matrix (Renuva) evidence for Hand dorsum volume loss

B 51.5 / 100 Insufficient 1 RCT/meta · 0 clinical/observational · 1 case · 2 total

Insufficient evidence

There is not yet enough PubMed evidence for this combination. The procedure exists, but research on this indication may be scarce.

Grade combines the quantity and quality of the research, while direction is a separate signal showing how the papers assess effectiveness.

Includes meta-analysis/SR Median year 2025 Last 5 years 100%

Known in Korea as

renuva

Procedure and brand names vary, but the evidence above applies to the same procedure mechanism.

Key papers

tier1 Current Applications and Indications of Allograft Adipose Matrix: A Systematic Review. Plastic and reconstructive surgery · 2025 · PMID 41056060

Abstract summary (English) BACKGROUND: Autologous fat transfer remains a staple in aesthetic and reconstructive surgery because of its regenerative capacity and tissue integration. However, limitations such as donor-site morbidity and unpredictable volume retention persist. Allograft adipose matrix (AAM), a product made from human fat tissue that serves as a natural scaffold to promote adipogenesis, offers a promising alternative, serving as...

Journal Article, Systematic Review

View on PubMed

tier3 Real-World Clinical Experience With an Allograft Adipose Matrix for Replacing Volume Loss in Face, Hands, and Body. Journal of cosmetic dermatology · 2024 · PMID 39291701

Abstract summary (English) INTRODUCTION: Real-world experience using an allograft adipose matrix (AAM) (Renuva) is presented as a series of seven cases demonstrating successful use of the matrix by nine expert cosmetic physicians across the United States. AAM is donated tissue that is aseptically processed without terminal irradiation into a transplantable adipose matrix that functions as a natural, versatile, and nonimmunogenic cushioning...

Journal Article, Case Reports

View on PubMed

Suggested interpretation

Limited evidence

← Other indications for the same procedure group | Other procedures for the same indication →

Adipose matrix (Renuva) evidence for Hand dorsum volume loss

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