GLASS LAB · Medical Aesthetics Evidence Index 303 cells · 19,226 papers · 5,969 top-tier evidence

Skin Quality · Facial dehydration / dry skin

HA skin booster evidence for Facial dehydration / dry skin

C 47.5 / 100 Supported 1 RCT/meta · 0 clinical/observational · 0 case · 3 total
Early-stage evidence

This is an early evidence stage based mainly on observational studies and case reports. Use it as supplementary reference, and follow your doctor's judgment for treatment decisions.

Grade combines the quantity and quality of the research, while direction is a separate signal showing how the papers assess effectiveness.

Median year 2023 Last 5 years 100% Positive results 100%

Known in Korea as

레티젠필메드물광주사스킨바이브스킨바이브 (booster)

Procedure and brand names vary, but the evidence above applies to the same procedure mechanism.

Key papers

tier1 A hyaluronic acid-based micro-filler improves superficial wrinkles and skin quality: a randomized prospective controlled multicenter study. The Journal of dermatological treatment · 2023 · PMID 37577796

Abstract summary (English) BACKGROUND: NCTF®135HA is a bio-revitalizing solution containing hyaluronic acid designed to compensate for skin dehydration, fatigue, and fine wrinkles associated with endogenous and environmental aging. METHODS: We conducted a randomized, active-controlled study to evaluate the efficacy and tolerability of NCTF®135HA injections on the face (crow's feet), neck, and décolleté regions. Subjects were randomly assigned...

Randomized Controlled Trial, Multicenter Study, Journal Article

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tier_other The efficacy of intradermal hyaluronic acid filler as a skin quality booster: A prospective, single-center, single-arm pilot study. Journal of cosmetic dermatology · 2023 · PMID 37705328

Abstract summary (English) BACKGROUND: The use of "skin boosters" comprised of hyaluronic acid (HA)-based fillers to improve skin quality has gained popularity recently, especially in individuals interested in skin rejuvenation. AIM: This study aimed to evaluate the efficacy and safety of intradermal micropuncture injections of HA-based gel filler combined with lidocaine (BYRYZN® SKINBOOSTER HA, ACROSS Co., Ltd., Gangwon-do, Korea)....

Journal Article

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tier_other Combined Bipolar Radiofrequency and Non-Crosslinked Hyaluronic Acid Mesotherapy Protocol to Improve Skin Appearance and Epidermal Barrier Function: A Pilot Study. Pharmaceuticals (Basel, Switzerland) · 2023 · PMID 37631060

Abstract summary (English) BACKGROUND: Age-associated changes in epidermal hydration, pigmentation, thickness and cell renewal influence skin appearance and can lead to laxity, dryness and poor skin tone. The aim of this pilot study was to assess the synergistic effects of a new bipolar radiofrequency plus non-crosslinked hyaluronic acid (HA) mesotherapy protocol compared with radiofrequency alone on skin appearance and markers of epidermal...

Journal Article

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Suggested interpretation

Limited evidence

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