GLASS LAB · Medical Aesthetics Evidence Index 303 cells · 19,226 papers · 5,969 top-tier evidence

Intimate · Vaginal laxity

Vaginal laxity RF evidence for Vaginal laxity

B 57.5 / 100 Supported 13 RCT/meta · 5 clinical/observational · 0 case · 44 total
Good evidence · positive conclusion

There is a relatively good level of clinical evidence, and a majority of papers support its effectiveness.

Grade combines the quantity and quality of the research, while direction is a separate signal showing how the papers assess effectiveness.

Includes meta-analysis/SR Median year 2021 Last 5 years 61% Positive results 64% Negative results 3 Korea/Asia 2

Known in Korea as

비비브

Procedure and brand names vary, but the evidence above applies to the same procedure mechanism.

Key papers

tier1 Vaginal Wall Thickness Measurement by 2D-Ultrasound and Pelvic Floor Muscle Morphometry by 4D-Ultrasound in Women With Vaginal Laxity Treated With Radiofrequency or Pelvic Floor Muscle Training. Neurourology and urodynamics · 2025 · PMID 39887781

Abstract summary (English) AIM: To compare the vaginal wall thickness (VWT) measurement by two-dimensional ultrasound (2D-US) and pelvic floor muscle morphometry by four-dimensional translabial ultrasound (4D-TLUS) in women with vaginal laxity (VL) who underwent treatment with radiofrequency (RF) or pelvic floor muscle training (PFMT) after 30 days and 6 months. METHODS: A secondary analysis of a randomized clinical trial that occurred...

Journal Article, Randomized Controlled Trial, Comparative Study

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tier1 Pelvic floor muscle training vs radiofrequency for women with vaginal laxity: randomized clinical trial. The journal of sexual medicine · 2024 · PMID 38972663

Abstract summary (English) BACKGROUND: Vaginal laxity (VL) is a complaint of excessive vaginal looseness with a prevalence ranging from 24% to 38% across studies. AIM: The study sought to compare the effect of radiofrequency (RF) and pelvic floor muscle training (PFMT) on the treatment of women with VL. METHODS: From February 2020 to December 2021, a prospective, parallel, noninferiority, randomized clinical trial was carried out in women ≥18...

Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't, Equivalence Trial

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tier1 Evaluating the Effectiveness of Radiofrequency Therapy and Manual Pelvic Fascial Release in Treating Myofascial Pelvic Pain. International urogynecology journal · 2024 · PMID 38722560

Abstract summary (English) INTRODUCTION AND HYPOTHESIS: Myofascial pelvic pain (MFPP), characterized by sensitive trigger points in the pelvic floor muscles, leads to chronic pain and affects various aspects of life. Despite the availability of different treatment modalities, there is limited comparative research on their effectiveness. This study compares radiofrequency (RF) therapy and myofascial manual therapy (MMT) in treating MFPP.

Journal Article, Comparative Study, Randomized Controlled Trial, Research Support, Non-U.S. Gov't

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tier1 Treatment of women with vaginal laxity: systematic review with meta-analysis. The journal of sexual medicine · 2024 · PMID 38508858

Abstract summary (English) BACKGROUND: Despite several treatments that have been used for women reporting vaginal laxity (VL), to our knowledge no systematic review is available on the topic so far. AIM: In this study, we sought to summarize the best available evidence about the efficacy and safety of interventions for treating VL, whether conservative or surgical. METHODS: A comprehensive search strategy was performed in Medline, Embase,...

Systematic Review, Journal Article, Meta-Analysis, Research Support, Non-U.S. Gov't

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tier1 Efficacy and safety of a device that combines multipolar radiofrequency with pulsed electromagnetic field for the treatment of vulvovaginal atrophy: a randomized, sham-controlled trial. The journal of sexual medicine · 2024 · PMID 38286753

Abstract summary (English) BACKGROUND: Vulvovaginal atrophy (VVA) negatively affects the sexual well-being and quality of life of postmenopausal women, yet it is underreported and undertreated. AIM: The study sought to investigate the efficacy and safety of a nonablative, noncoagulative multipolar radiofrequency (RF) and pulsed electromagnetic field-based device (PEMF) in treatment of symptoms related to VVA. METHODS: Seventy-six women ≥19...

Randomized Controlled Trial, Multicenter Study, Journal Article, Research Support, Non-U.S. Gov't

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tier1 A Randomized, Placebo-Controlled Trial Evaluating the Single and Combined Efficacy of Radiofrequency and Hybrid Fractional Laser for Nonsurgical Aesthetic Genital Procedures in Post-Menopausal Women. Aesthetic surgery journal · 2022 · PMID 35882474

Abstract summary (English) BACKGROUND: The efficacy of interventions that provide long-term relief of genitourinary symptoms of menopause has not been determined. OBJECTIVES: The authors sought to evaluate radiofrequency and hybrid fractional laser (HFL) treatments for menopausal vulvovaginal symptoms. METHODS: Thirty-one postmenopausal women completed all treatments and at least 1 follow-up.

Randomized Controlled Trial, Journal Article

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tier1 The effect of dynamic quadripolar radiofrequency on genitourinary atrophy and sexual satisfaction: A systematic review and meta-analysis. Medicine · 2022 · PMID 36221421

Abstract summary (English) BACKGROUND: Physiologic processes such as childbirth and menopause can alter vulvovaginal aesthetic appearance, reduce sexual satisfaction, and cause symptoms of vulvovaginal atrophy which affects a woman's quality of life. There is debate about whether dynamic quadripolar radiofrequency (DQRF) can be used to improve such conditions. We conducted a meta-analysis of studies among patients undergoing treatment with...

Journal Article, Meta-Analysis, Systematic Review

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tier1 Comparative effects of fractional radiofrequency and microneedling on the genitalia of postmenopausal women: Histological and clinical changes. Clinics (Sao Paulo, Brazil) · 2022 · PMID 36183506

Abstract summary (English) OBJECTIVES: The authors aimed to evaluate clinical and histological changes induced by Fractional Radiofrequency (FRF) and microneedling in vulvar tissue. METHODS: Thirty postmenopausal women were randomly divided into G1 (FRF) and G2 (microneedling) groups. Sub-ablative FRF was executed using disposable fractionated electrodes with an intensity of 8 mJ.

Journal Article, Randomized Controlled Trial

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tier1 The efficacy and safety of a combined multipolar radiofrequency with pulsed electromagnetic field technology for the treatment of vaginal laxity: a double-blinded, randomized, sham-controlled trial. Lasers in medical science · 2021 · PMID 34647191

Abstract summary (English) Non-invasive vaginal rejuvenation with radiofrequency (RF) and lasers devices have gained popularity, but well-designed studies confirming their effectiveness are lacking. The aim of this study was to compare the efficacy and safety of a multipolar RF and pulsed electromagnetic field-based device (PEMF) versus sham for vaginal laxity. Thirty-two premenopausal females with ≥ 1 vaginal delivery and self-reported...

Journal Article, Randomized Controlled Trial

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tier1 Microablative radiofrequency versus pelvic floor muscle training for stress urinary incontinence: a randomized controlled trial. International urogynecology journal · 2021 · PMID 33837797

Abstract summary (English) INTRODUCTION AND HYPOTHESIS: The efficacy of radiofrequency (RF) in stress urinary incontinence (SUI) is as yet unknown. The aim was to compare the effect of fractional microablative RF and pelvic floor muscle training (PFMT) against the combination of both therapies (RF + PFMT) in the SUI and on genitourinary syndrome (GSM). METHODS: This was a three-arm randomized clinical trial including 117 climacteric women...

Journal Article, Randomized Controlled Trial

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