PLLA filler (Sculptra) evidence for Decollete laxity

Abstract summary (English) BACKGROUND: Injectable fillers for soft tissue augmentation stand out as one of the most favored procedures in the field of aesthetic medicine, especially in addressing the clinical signs of skin aging. Among soft tissue fillers, non-permanent fillers have been safely used in numerous medical applications for several decades. AIMS: The aim of this post-market observational, open-label, uncontrolled, multicentered,...

Journal Article, Multicenter Study, Observational Study

Abstract summary (English)

Injectable soft-tissue augmentation agents have become popular alternatives to surgical procedures for the aging face and body. In contrast to temporary, space-occupying replacement fillers such as collagen-based and hyaluronic acid products, poly-l-lactic acid (PLLA) has been demonstrated to gradually promotes deposition of collagen via a biostimulatory response, with therapeutic effects lasting approximately...

Journal Article, Review

Abstract summary (English) BACKGROUND: Photodamaged skin of the chest is characterized by skin laxity, lines/wrinkles, hyperpigmentation, erythema, tactile roughness, atrophy, and telangiectasias. METHODS: A MEDLINE search was performed on combination treatments in chest rejuvenation, and the results are summarized. Practical applications for these combinations of procedures are discussed.

Journal Article, Review

Abstract summary (English) BACKGROUND: Patients increasingly request rejuvenation of the aging and photodamaged décolletage. Rhytides in this area can be addressed with injectables such as poly-L-lactic acid and hyaluronic acid products and energy-based devices, such as fractionated ablative and nonablative lasers and microfocused ultrasound with visualization. METHODS: This article will review the anatomy of the chest wall as it pertains to...

Journal Article, Review

Abstract summary (English) BACKGROUND: Aging of the face, neck, and décolletage is a multifactorial process involving epidermal photodamage and loss of soft tissue and bony volume. Multilevel rejuvenation of these areas can be obtained by enhancing volume restoration, neocollagenesis, and tissue contraction with combined efficacy of poly-L-lactic acid (PLLA) and microfocused ultrasound (MFU, Ultherapy) treatments. METHODS: The authors...

Journal Article, Review

Abstract summary (English) UNLABELLED: With the recognition of the key role of volume loss in the facial aging process, injectable dermal fillers and volumizers have become increasingly important treatment options for recontouring and rejuvenating the aging face. While replacement fillers effectively correct individual lines and wrinkles, volumizing agents that replace collagen provide a longer-lasting, volume-based alternative. Poly-L-lactic...

Journal Article, Review

Abstract summary (English) We present a case of 72-year-old that arrived at our emergency department following breaking of a dermal cannula used to inject a poly-L-lactic acid (PLLA) to the décolleté by an aesthetic practitioner. She had a history of previous radiation to the breast after a lumpectomy. The cannula was removed using fluoroscopy guidance.

Case Reports, Letter

Abstract summary (English) BACKGROUND: Poly-L-lactic acid (PLLA-SCA) was approved for facial aesthetic use in the USA in 2009. Nonfacial aesthetic treatment using PLLA-SCA, a collagen-stimulating injectable implant, is a frequent clinical practice, and initial studies support its safety. OBJECTIVES: The objective of this study was to evaluate the safety of PLLA-SCA when used in nonfacial areas in real clinical practice in the USA.

Journal Article

Abstract summary (English) Injectable poly-L-lactic acid (PLLA) is a biodegradable synthetic polymer that stimulates collagen production, leading to gradual volume restoration. The treatment of sagging skin in body areas is still a big challenge, as there are few aesthetic procedures aiming to improve it. This article provides recommendations on the use of PLLA in the treatment of skin laxity in off-face areas, as the neck, décolletage, arms,...

Journal Article

Abstract summary (English) BACKGROUND: Poly-L-lactic acid (PLLA) is a biostimulatory filler approved for use in HIV lipoatrophy as well as cosmetic improvement in facial folds and wrinkles in immunocompetent patients. Similar to the face and hands, the décolletage is commonly subject to photodamage and the resulting appearance of rhytids and crepiness, which could benefit from PLLA treatment. OBJECTIVES: The objective of the study was to...

Journal Article