GLASS LAB · Medical Aesthetics Evidence Index 303 cells · 19,226 papers · 5,969 top-tier evidence

Lifting / Laxity · Submental / neck laxity

Pdo PCL PLLA thread lifting evidence for Submental / neck laxity

C 35.1 / 100 Insufficient 1 RCT/meta · 0 clinical/observational · 2 case · 8 total
Early-stage evidence

This is an early evidence stage based mainly on observational studies and case reports. Use it as supplementary reference, and follow your doctor's judgment for treatment decisions.

Grade combines the quantity and quality of the research, while direction is a separate signal showing how the papers assess effectiveness.

Median year 2026 Last 5 years 100% Positive results 100% Korea/Asia 1

Known in Korea as

돌기실모노실민트실압토스잼버실LSCO아이쓰레드맞춤 실리프팅실루엣 Fit실루엣 소프트

Procedure and brand names vary, but the evidence above applies to the same procedure mechanism.

Key papers

tier_other Retrograde approach to mid-face thread lift with reverse temporal vectors: an innovative insight into the conventional approach. Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology · 2026 · PMID 41902759

Abstract summary (English) The retrograde approach to mid-face thread lift, utilizing reverse temporal vectors, offers an innovative advancement in minimally invasive facial rejuvenation. This study evaluates its efficacy and safety in 20 female patients aged 30-60 years presenting with moderate midface ptosis but minimal jowling and neck laxity. The technique involves inserting poly L-lactide-co-ε-caprolactone bi-directional threads into...

Journal Article

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tier_other Absorbable Barbed Threads for Lower Facial Soft-Tissue Repositioning in Asians. Dermatology and therapy · 2021 · PMID 34218425

Abstract summary (English) INTRODUCTION: Asian patients often seek to address lower facial aging through clinical interventions that increase anterior projection and jawline contouring. The Definisse™ (also known as Happy Lift™) thread lift treatment uses barbed absorbable threads to suspend tissues and induce biostimulation. We evaluated the efficacy and safety of absorbable barbed threads for lower facial reshaping in Thai patients.

Journal Article

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Suggested interpretation

For reference

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