Pigment · Solar lentigo / sunspot
Nonablative fractional resurfacing evidence for Solar lentigo / sunspot
This is an early evidence stage based mainly on observational studies and case reports. Use it as supplementary reference, and follow your doctor's judgment for treatment decisions.
Grade combines the quantity and quality of the research, while direction is a separate signal showing how the papers assess effectiveness.
Median year 2020 Last 5 years 33% Positive results 67%
Known in Korea as
Procedure and brand names vary, but the evidence above applies to the same procedure mechanism.
Key papers
tier1 Tripeptide and hexapeptide topical as adjunct to nonablative fractional resurfacing for photodamage: A randomized split-face trial.
Abstract summary (English) BACKGROUND: Topical adjuncts have been investigated to improve clinical outcomes associated with laser resurfacing for photodamage and cutaneous aging. One such product is a tripeptide/hexapeptide serum, which has been shown to increase dermal collagen and elastin as well as improve postprocedural recovery following treatments. AIMS: A randomized, blinded, split-face, comparative trial was performed to assess the...
Journal Article, Randomized Controlled Trial
View on PubMedtier2 1,927-nm fractional thulium fiber laser for the treatment of nonfacial photodamage: a pilot study.
Abstract summary (English) BACKGROUND: A 1,927-nm wavelength was recently added to the 1,550-nm erbium-doped fiber laser. This wavelength possesses a higher absorption coefficient for water than the 1,550-nm, conferring greater ability to target epidermal processes. OBJECTIVE: To evaluate the efficacy and safety of a novel 1,927-nm fractional thulium fiber laser in the treatment of nonfacial photodamage.
Evaluation Study, Journal Article
View on PubMedtier3 Investigating the efficacy of a fractionated 1927 nm laser for diffuse dyspigmentation and actinic changes.
Abstract summary (English) OBJECTIVES: Facial actinic irregularities are frequent targets for noninvasive, energy-based treatment. These irregularities are multifactorial and driven by both intrinsic factors such as aging, genetics, and hormone exposure, and extrinsic factors, such as UV exposure. Clinically, this photodamage manifests as dyschromic skin disorders like melasma and actinic features such as solar lentigines.
Case Reports, Research Support, Non-U.S. Gov't, Journal Article
View on PubMedtier3 Rejuvenation of the male scalp using 1,927 nm non-ablative fractional thulium fiber laser.
Abstract summary (English) OBJECTIVE: The male scalp undergoes extensive photodamage due to a high prevalence of androgenic alopecia and exposure to ultraviolet radiation. This photodamage presents as solar lentigines, fine rhytides, and keratosis, and can prematurely age a patient. In this study, we demonstrate the safety and efficacy of the fractionated 1,927 nm thulium fiber laser using high density and high energy settings to achieve...
Case Reports, Journal Article
View on PubMedtier_other Optimizing Outcomes With the 1550/1927 nm Dual Wavelength Non-Ablative Fractional Laser: Experienced User Recommendations.
Abstract summary (English) BACKGROUND: Fractional laser treatment was introduced in 2004 as a non-invasive technique to treat sun-damaged and aging skin. Since then, numerous ablative and non-ablative photothermolysis technologies and devices have been introduced, increasing the options for clinicians and patients but also increasing the complexity regarding which system to use and the techniques to optimize outcomes. No two devices are the...
Journal Article
View on PubMedtier_other Q-Switched Alexandrite Laser-induced Chrysiasis.
Abstract summary (English) BACKGROUND: Chyriasis is an uncommon side effect that occurs in patients who are receiving prolonged treatment with either intravenous or intramuscular gold as a distinctive blue-gray pigmentation of light-exposed skin. Laser-induced chrysiasis is a rarely described phenomenon in individuals who have received systemic gold and are subsequently treated with a Q-switched laser. PURPOSE: To describe the characteristics...
Journal Article
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