Inflammatory / Specialty · Actinic keratosis
Nonablative fractional resurfacing evidence for Actinic keratosis
There is a relatively good level of clinical evidence, and a majority of papers support its effectiveness.
Grade combines the quantity and quality of the research, while direction is a separate signal showing how the papers assess effectiveness.
Includes meta-analysis/SR Median year 2014 Last 5 years 25% Positive results 88%
Known in Korea as
Procedure and brand names vary, but the evidence above applies to the same procedure mechanism.
Key papers
tier1 Evidence-Based Clinical Practice Guidelines for Laser-Assisted Drug Delivery.
Abstract summary (English) IMPORTANCE: Laser-assisted drug delivery (LADD) is used for various medical and cosmetic applications. However, there is insufficient evidence-based guidance to assist clinicians performing LADD. OBJECTIVE: To develop recommendations for the safe and effective use of LADD.
Systematic Review, Journal Article, Research Support, Non-U.S. Gov't
View on PubMedtier2 Fractional Q-switched 1,064-nm laser for the treatment of photoaged-photodamaged skin.
Abstract summary (English) INTRODUCTION: The Q-switched 1064-nm laser is associated with rapid vaporization and thermal expansion stresses leading to skin mechanical damage and is typically used for correction of exogenous and endogenous deep pigmentation. Giving the common place of fractional, infrared-domain milliseconds non-ablative lasers in aesthetic dermatology, a novel non-ablative fractional Q-switched 1,064-nm laser was studied for...
Clinical Trial, Journal Article, Research Support, Non-U.S. Gov't
View on PubMedtier2 Treatment of actinic keratoses and photodamage with non-contact fractional 1540-nm laser quasi-ablation: an ex vivo and clinical evaluation.
Abstract summary (English) The main use of non-ablative fractional photothermolysis today is for the improvement of wrinkles and scars. The purpose of this work was to evaluate the effect of a "classic" non-ablative fractional 1540 nm on facial photodamaged skin and actinic keratoses. Seventeen patients with facial actinic keratoses (AKs) and photodamage underwent two or three laser treatments with fractional 1540-nm erbium glass laser at...
Clinical Trial, Journal Article
View on PubMedtier0_review Current Trends and Future Directions of the Dual 1550-nm Erbium Glass Fiber and 1927-nm Thulium Fiber Non-Ablative Fractional Laser System.
Abstract summary (English) OBJECTIVES: To synthesize current evidence and trends supporting the dual 1550-nm erbium glass fiber and 1927-nm thulium fiber non-ablative fractional laser system's mechanism of action and proven efficacy and safety profile in addressing aging skin concerns. METHODS: A review of current evidence and expert consensus was conducted to evaluate the 1550/1927-nm dual laser system. The analysis focused on the 1550 and...
Journal Article, Review
View on PubMedtier_other Nonablative fractional laser therapy for treatment of actinic keratosis with 3-months follow-up.
Abstract summary (English) BACKGROUND: Actinic keratosis (AK) is a common skin disorder that is treated with different treatment modalities. AIMS: The aim of this study was to assess the therapeutic effect of a 1540-nm nonablative fractional laser on the AK. METHODS: Ten patients with 31 AK were included in the study according to the inclusion and exclusion criteria.
Journal Article
View on PubMedtier_other Laser treatment and its implications for photodamaged skin and actinic keratosis.
Abstract summary (English) Treatment of widespread actinic keratoses (AKs) and extensive photodamage is a challenge. One of the treatment options is laser therapy, whereby physicians have the option of using ablative lasers (CO2 and Erbium Yttrium Aluminium Garnet) or nonablative fractional laser systems. With ablative laser systems, the superficial layers of the skin are ablated, including epidermal and superficial dermal actinic damage.
Journal Article
View on PubMedtier_other Non-ablative fractional resurfacing in combination with topical tretinoin cream as a field treatment modality for multiple actinic keratosis: a pilot study and a review of other field treatment modalities.
Abstract summary (English) BACKGROUND: Actinic keratoses (AK) are premalignant lesions occurring mainly in sun-damaged skin. Current topical treatment options for AK and photo-damaged skin such as liquid nitrogen and electrosurgery are not suitable for field treatment. Otherwise, therapies suitable for field treatment bring along considerable patient discomfort.
Journal Article
View on PubMedtier_other Nonablative fractional photothermolysis for facial actinic keratoses: 6-month follow-up with histologic evaluation.
Abstract summary (English) BACKGROUND: A number of epidermal and papillary dermal skin conditions can be treated safely and effectively with fractional photothermolysis (FP). OBJECTIVE: We sought to evaluate the effectiveness of FP with a 1550-nm fractionated erbium-doped fiber laser for the treatment of facial actinic keratoses (AKs). METHODS: Fourteen men, ages 59 to 79 years, underwent 5 laser treatments (2- to 4-week intervals) at an...
Journal Article, Research Support, Non-U.S. Gov't
View on PubMedPersonalized evidence report
Tell us more about your concern
and the Glass Lab bot will build a personalized report for you.
Based on the Nonablative fractional resurfacing · Actinic keratosis information on this page, we'll email you an evidence summary tailored to your skin condition and treatment stage.