GLASS LAB · Medical Aesthetics Evidence Index 303 cells · 19,226 papers · 5,969 top-tier evidence

Lifting / Laxity · Striae distensae

Monopolar RF lifting evidence for Striae distensae

B 61.3 / 100 Supported 8 RCT/meta · 5 clinical/observational · 0 case · 22 total
Good evidence · positive conclusion

There is a relatively good level of clinical evidence, and a majority of papers support its effectiveness.

Grade combines the quantity and quality of the research, while direction is a separate signal showing how the papers assess effectiveness.

Includes meta-analysis/SR Median year 2018 Last 5 years 30% Positive results 78% Korea/Asia 4

Known in Korea as

덴서티볼뉴머세르프써마지올리지오올타이트울써마지튠라이너튠페이스올리지오X

Procedure and brand names vary, but the evidence above applies to the same procedure mechanism.

Key papers

tier1 Comparing fractional microneedle radiofrequency and fractional CO2 laser for striae distensae treatment: a systematic review and meta-analysis. Lasers in medical science · 2024 · PMID 39516426

Abstract summary (English) Striae distensae (SD) are a prevalent dermatological concern of women and approximately 90% of pregnant women experience these stretch marks. Fractional microneedle radiofrequency (FMR) and fractional CO2 laser (FCL) have gained substantial attention in the treatment of SD. In clinical studies, a clear superiority between FMR and FCL treatments is not found due to limited studies and sample sizes.

Journal Article, Systematic Review, Meta-Analysis, Comparative Study

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tier1 Comparing Energy-Based Devices for Striae Improvement: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2024 · PMID 38820425

Abstract summary (English) BACKGROUND: Striae distensae (SD) are cutaneous lesions that are caused by hormones or mechanical stress leading to rapid expansion of skin. Therefore, SD are now a cosmetic concern. However, improving SD is notoriously difficult.

Journal Article, Systematic Review, Comparative Study, Research Support, Non-U.S. Gov't, Network Meta-Analysis

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tier1 Comparative effectiveness of different therapies for treating striae distensae: A systematic review and network meta-analysis. Medicine · 2020 · PMID 32991422

Abstract summary (English) BACKGROUND: Striae distensae (SD) are common and aesthetically undesirable dermal lesions. The aim of this study is to comprehensively evaluate the effectiveness of different therapies in treating striae distensae using network meta-analysis. METHODS: A systematic search of electronic databases up to December 1, 2019 was conducted.

Journal Article, Systematic Review, Network Meta-Analysis

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tier1 Efficacy and Safety of a Sublative Bipolar Fractional Radiofrequency System Combined With Topical Tretinoin in Treating Striae Gravidarum: A Randomized Pilot Study. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2019 · PMID 30893166

Abstract summary (English) BACKGROUND: Striae gravidarum is a common skin condition resulting after pregnancy, caused by fibroblast dysfunction. Although not considered a disease, it may be considered cosmetically unpleasant to sufferers and remains as a therapeutic challenge to date. OBJECTIVE: To evaluate the efficacy and safety of a sublative bipolar fractional radiofrequency (FRF) system, associated with 0.1% topical tretinoin, in...

Journal Article, Randomized Controlled Trial

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tier1 Comparative study between: Carboxytherapy, platelet-rich plasma, and tripolar radiofrequency, their efficacy and tolerability in striae distensae. Journal of cosmetic dermatology · 2018 · PMID 29921041

Abstract summary (English) BACKGROUND: Striae distensae are very common cutaneous disorders that produce great psychological stress for women. OBJECTIVE: measure and compare between efficacy and tolerability of three modalities for treatment of striae distensae. PATIENTS AND METHODS: Forty-five female patients with striae distensae were randomly selected from the outpatient dermatology clinics of Al-Zahra university Hospital within 6 months...

Comparative Study, Journal Article, Randomized Controlled Trial

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tier1 The use of energy devices in the treatment of striae: a systematic literature review. The Journal of dermatological treatment · 2018 · PMID 30049244

Abstract summary (English) BACKGROUND: Striae distensae are caused by rapid stretching of the skin. They are often secondary to obesity or pregnancy and can lead to significant cosmetic disfigurement. AIM: To determine the efficacy, indications, and side effects of commonly used energy devices in the treatment of striae.

Journal Article, Systematic Review

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tier1 Fractionated bipolar radiofrequency and bipolar radiofrequency potentiated by infrared light for treating striae: A prospective randomized, comparative trial with objective evaluation. Lasers in surgery and medicine · 2016 · PMID 27020000

Abstract summary (English) BACKGROUND AND OBJECTIVE: Very few treatments for striae are based on prospective randomized trials. The objective of this study was to assess the efficacy of bipolar fractional radiofrequency and bipolar radiofrequency potentiated with infrared light, alone or combined, for treating abdominal stretch marks. STUDY DESIGN/MATERIALS AND METHODS: Bicentric prospective interventional randomized controlled trial in the...

Comparative Study, Journal Article, Multicenter Study, Randomized Controlled Trial, Research Support, Non-U.S. Gov't

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tier1 Striae distensae: a comprehensive review and evidence-based evaluation of prophylaxis and treatment. The British journal of dermatology · 2014 · PMID 24125059

Abstract summary (English) Striae distensae are an extremely common, therapeutically challenging form of dermal scarring. Risk factors have been reported but much remains to be understood about their epidemiology, diagnosis and treatment. Up-to-date knowledge of the scientific research and the evidence behind both preventative and therapeutic agents are vital in order to understand striae and to offer patients the best therapeutic...

Journal Article, Systematic Review

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tier2 Efficacy and safety of bipolar fractional radiofrequency vs. 2940-nm Er:YAG ablative fractional laser in striae distensae treatment: A split abdomen study. Journal of cosmetic dermatology · 2024 · PMID 38385807

Abstract summary (English) BACKGROUND: Striae distensae (SD) is a challenging cosmetic condition. Ablative fractional laser (AFL) is an effective method for treating SD. Recently, fractional radiofrequency (FRF) has been shown to be a promising treatment for SD; however, few studies have shown the differences between FRF and AFL in the treatment of SD.

Journal Article, Comparative Study

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tier2 Comparative study between the efficacy of fractional micro-needle radiofrequency and fractional CO2 laser in the treatment of striae distensae. Lasers in medical science · 2019 · PMID 31044363

Abstract summary (English) Striae distensae (SD) cause a cosmetic problem to many patients. Recently, fractional micro-needle radiofrequency (FMR) device has been introduced in treatment of SD. Also, fractional CO2 laser has been used as a resurfacing laser technique in the treatment of SD.

Clinical Trial, Comparative Study, Journal Article

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Suggested interpretation

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