GLASS LAB · Medical Aesthetics Evidence Index 303 cells · 19,226 papers · 5,969 top-tier evidence

Body / Fat · Cellulite dimpling

Monopolar RF lifting evidence for Cellulite dimpling

B 54.0 / 100 Supported 5 RCT/meta · 9 clinical/observational · 2 case · 52 total
Good evidence · positive conclusion

There is a relatively good level of clinical evidence, and a majority of papers support its effectiveness.

Grade combines the quantity and quality of the research, while direction is a separate signal showing how the papers assess effectiveness.

Includes meta-analysis/SR Median year 2015 Last 5 years 23% Positive results 64% Negative results 1 Korea/Asia 2

Known in Korea as

덴서티볼뉴머세르프써마지올리지오올타이트울써마지튠라이너튠페이스올리지오X

Procedure and brand names vary, but the evidence above applies to the same procedure mechanism.

Key papers

tier1 Does electrophysical agents work for cellulite treatment? a systematic review of clinical trials. Lasers in medical science · 2024 · PMID 38695965

Abstract summary (English) UNLABELLED: Cellulite, a perceived alteration in skin topography, is predominantly found in adipose tissue-rich body regions such as the hips, buttocks, thighs, and abdomen. Contrary to common belief, the etiology and pathophysiology of cellulite are not well-established or universally agreed upon. This lack of understanding about the actual etiology of cellulite directly influences the selection of suitable...

Systematic Review, Journal Article

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tier1 Fractional radiofrequency treatment in acne scars: Systematic review of current evidence. Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology · 2016 · PMID 27592504

Abstract summary (English) Fractional radiofrequency (FRF) is renowned for its use in cosmetic dermatology, with regard to the treatment of rhytides, striae, scarring and cellulite. We have systemically analysed its evidence for the use of FRF in acne scars. Our search identified 15 articles, one single-blinded randomised controlled trial, two split-face trials and thirteen prospective clinical studies, mostly single-centred.

Journal Article, Systematic Review

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tier1 Complementary clinical effects of topical tightening treatment in conjunction with a radiofrequency procedure. Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology · 2014 · PMID 24927068

Abstract summary (English) UNLABELLED: Abstract Background: Skin laxity and cellulite on the buttocks and thighs are two common cosmetic concerns. Skin tightening with radiofrequency (RF) devices has become increasingly popular. OBJECTIVE: The purpose of this study is to evaluate the efficacy and safety of a topical skin laxity tightening agent when used in combination with an RF device.

Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't

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tier1 Unipolar radiofrequency treatment to improve the appearance of cellulite. Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology · 2008 · PMID 18788033

Abstract summary (English) BACKGROUND: Previous studies suggest that radiofrequency (RF) energy may be effective as a treatment for cellulite. OBJECTIVE: This bilateral paired blinded comparative study assesses the efficacy and safety of a unipolar RF device for improving the appearance of cellulite using a new quantitative cellulite grading system. METHODS: In this randomized, blinded, split-design study, 10 individuals (aged 32-57 years)...

Journal Article, Randomized Controlled Trial

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tier1 A single center, randomized, comparative, prospective clinical study to determine the efficacy of the VelaSmooth system versus the Triactive system for the treatment of cellulite. Lasers in surgery and medicine · 2006 · PMID 17163477

Abstract summary (English) BACKGROUND AND OBJECTIVES: One area of cosmetic concern for women of all races is the unsightly appearance of cellulite in the buttocks area and lower extremities. Two modern technological advances claim to improve cellulite and provide reproducible results, TriActive and VelaSmooth. The TriActive laser is intended to reduce the appearance of cellulite through the combination of low-energy diode laser, contact...

Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't

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tier2 Effectiveness of Body Remodeling and Cellulite Appearance Improvement Treatments in the Thighs Using Symmed Radiofrequency Device. Journal of cosmetic dermatology · 2025 · PMID 39815666

Abstract summary (English) BACKGROUND: Aging associated with the passage of time causes alterations in subcutaneous tissues and the overall appearance of the skin that generate aesthetic unconformities in people. Within the wide range of available techniques on the market, radiofrequency (RF) diathermy has emerged as one of the most used non-invasive methods to combat them. OBJECTIVE: This clinical trial aims to determine and quantify the...

Journal Article, Clinical Trial

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tier2 Prospective Multicenter Clinical Trial of a Temperature-Controlled Subcutaneous Microneedle Fractional Bipolar Radiofrequency System for the Treatment of Cellulite. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2018 · PMID 30222637

Abstract summary (English) BACKGROUND: A bipolar fractional radiofrequency (RF) device was developed to generate cutaneous thermal injuries using a temperature-controlled microneedle electrode array. OBJECTIVE: Evaluate safety and efficacy of a novel subcutaneous microneedle RF for treatment of posterolateral thigh cellulite. METHODS: The study design was an institutional review board-approved multicenter clinical trial after a per-protocol...

Clinical Trial, Journal Article, Multicenter Study

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tier2 Clinical and histopathological study of the TriPollar home-use device for body treatments. European journal of dermatology : EJD · 2010 · PMID 20395192

Abstract summary (English) Professional non invasive treatments for body contouring based on radiofrequency (RF) became popular in aesthetic clinics due to proven efficacy and safety. A new home-use RF device for body treatments has been developed based on TriPollar technology. Our objective was to evaluate the TriPollar home-use device for circumference reduction, cellulite improvement and skin tightening using objective and subjective...

Comparative Study, Journal Article, Research Support, Non-U.S. Gov't

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tier2 Clinical and histopathological results following TriPollar radiofrequency skin treatments. Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology · 2009 · PMID 19408182

Abstract summary (English) INTRODUCTION: Skin laxity, wrinkles and cellulite are common aesthetic problems associated with the aging process. These symptoms are due to the weakening and thinning of dermal connective tissue and the enlargement of hypodermal fat cells. The aim of this study was to evaluate the safety and efficacy of the TriPollar RF technology in reducing fat and collagen regeneration.

Clinical Trial, Journal Article

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tier2 A multicenter study of cellulite treatment with a variable emission radio frequency system. Dermatologic therapy · 2009 · PMID 19222519

Abstract summary (English) Radio frequency (RF) systems have been reported as producing electrothermally mediated and subcutaneous effects. The present study evaluates a new approach to treat cellulite with a bipolar RF device. The buttocks of 50 patients were treated, 10 from each of five multinational centers with a novel bipolar RF technology set at 6 J/cm(3), which changes its frequency between 0.6 and 2.4 MHz according to impedance of...

Clinical Trial, Journal Article, Multicenter Study, Research Support, Non-U.S. Gov't

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Suggested interpretation

Strong evidence base

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