GLASS LAB · Medical Aesthetics Evidence Index 303 cells · 19,226 papers · 5,969 top-tier evidence

Healing / Recovery · Post-laser recovery

LED phototherapy evidence for Post-laser recovery

C 43.3 / 100 Supported 234 RCT/meta · 190 clinical/observational · 85 case · 1273 total
Early-stage evidence

This is an early evidence stage based mainly on observational studies and case reports. Use it as supplementary reference, and follow your doctor's judgment for treatment decisions.

Grade combines the quantity and quality of the research, while direction is a separate signal showing how the papers assess effectiveness.

Median year 2019 Last 5 years 38% Positive results 67% Negative results 2 Korea/Asia 3

Known in Korea as

스킨아우라

Procedure and brand names vary, but the evidence above applies to the same procedure mechanism.

Key papers

tier1 Efficacy of 1064-Nm Picosecond Nd: YAG Laser in Treating Facial Photoaging and Improving Skin Barrier Enhanced by a Multi-Beneficial Composition Formulation: A Blinded Randomized Clinical Trial Study. Journal of cosmetic dermatology · 2026 · PMID 42087413

Abstract summary (English) BACKGROUND: In recent years, skin photoaging has received increasing attention, and laser therapy has become the most commonly used treatment due to its safety and efficacy; emerging evidence suggests that adjunctive "integrated skincare" may enhance treatment benefits by reducing post-procedural reactions and supporting skin barrier repair. OBJECTIVE: The split-face, double-blind, randomized, placebo-controlled,...

Journal Article, Randomized Controlled Trial

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tier1 Local and systemic effects of low-level light therapy with light-emitting diodes to improve erythema after fractional ablative skin resurfacing: a controlled study. Lasers in medical science · 2018 · PMID 30074109

Abstract summary (English) Therapy with light-emitting diodes (LED) has been associated with the reduction of erythema and accelerated wound healing. LED phototherapy has been used in various clinical practices including post-laser wound healing enhancement. Fractional laser resurfacing is one of the popular dermatological procedures; however, the duration and degree of downtime may limit daily life activity and studies on the effect of LED...

Journal Article, Randomized Controlled Trial

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tier1 Therapeutic efficacy and safety of a 1927-nm fractionated thulium laser on pattern hair loss: an evaluator-blinded, split-scalp study. Lasers in medical science · 2018 · PMID 29340854

Abstract summary (English) Laser- or light-assisted therapies have been used to improve the perifollicular environment by upregulating the expression of growth factors and signaling molecules for hair restoration. The aim of our study was to preclinically and clinically evaluate the therapeutic efficacy and safety of a 1927-nm fractionated thulium laser on pattern hair loss (PHL). An in vivo hairless mouse study and an in vivo human skin...

Journal Article, Randomized Controlled Trial

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tier1 Effectiveness of a Nutraceutical During Non-Ablative 1927 nm Fractional Laser on Patients With Facial Hyperpigmentation and Photoaging. Journal of drugs in dermatology : JDD · 2017 · PMID 28628688

Abstract summary (English)

Background: Fractional lasers have been proven to treat hyperpigmentation and photoaging. Little research has been done on the effects of supplements on healing post-laser resurfacing. A nutraceutical could offer the benefit of faster healing of the skin and fewer side effects.

Objective: Evaluate the effectiveness of a nutraceutical associated with fractional 1927 nm laser in healing time and...

Journal Article, Randomized Controlled Trial

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tier1 Split treatment of photodamaged skin with KTP 532 nm laser with 10 mm handpiece versus IPL: a cheek-to-cheek comparison. Lasers in surgery and medicine · 2006 · PMID 16142765

Abstract summary (English) BACKGROUND AND OBJECTIVES: The treatment of photodamaged skin with potassium-titanyl-phosphate (KTP) laser and intense pulsed light (IPL) has been reported in several studies. Each device has strengths and weaknesses; however, patient and device variability have made it difficult to ascertain the optimal device for photorejuvenation. The objective of this study was to obtain a head-to-head comparison of IPL and KTP...

Journal Article, Randomized Controlled Trial

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tier2 Novel post-treatment care after ablative and fractional CO2 laser resurfacing. Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology · 2013 · PMID 24131071

Abstract summary (English) OBJECTIVE: This study evaluates a topical oxygen emulsion (TOE) to reduce adverse effects after skin rejuvenation with a fully ablative CO2 laser alone and in combination with a fractional ablative CO2 laser. MATERIALS AND METHODS: Patients (n = 100) seeking skin rejuvenation underwent CO2 laser resurfacing. Group A patients (n = 34) received a single deep fractional laser treatment followed by application of...

Clinical Trial, Journal Article

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tier2 A new modality for fractional CO2 laser resurfacing for acne scars in Asians. Lasers in medical science · 2012 · PMID 22618157

Abstract summary (English) Since fractional photothermolysis was first introduced in 2004, it has become a very popular procedure, especially with more and more ablative fractional laser systems and treatments. Fractional ablative laser has been shown to be very effective; however, it does not reach the efficacy of conventional ablative laser treatments in most instances. In an attempt order to make the fractional CO2 laser treatment more...

Clinical Trial, Journal Article

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tier2 New clinical outcomes utilizing a 1064-nm Nd:YAG laser for lipolysis of the torso oblique region. Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology · 2010 · PMID 20653346

Abstract summary (English) OBJECTIVES: The safety and efficacy of a 1064-nm Nd:YAG laser (Cynosure, Westford, USA) utilizing a 300-microm optical fiber and a 1-mm diameter micro-cannula were evaluated as a treatment for reduction in the appearance or elimination of unwanted fat in the lower back/flanks ('love handles'). In addition, the use of the laser for tightening the skin and collagen regeneration in the area of lipolysis was assessed...

Clinical Trial, Journal Article

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tier2 308-nm excimer laser for the treatment of alopecia areata in children. Pediatric dermatology · 2009 · PMID 19840308

Abstract summary (English) Alopecia areata (AA) is a common skin disease which is characterized by nonscarring localized or diffused hair loss. In this study we assessed the efficacy of 308-nm Excimer laser in the treatment of alopecia areata in children. A total of 9 children with 30 recalcitrant patches alopecia areata and two children with alopecia areata totalis were enrolled in this study which included seven male and four female...

Clinical Trial, Journal Article

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tier2 Novel model for evaluation of epidermal preservation and dermal collagen remodeling following photorejuvenation of human skin. Lasers in surgery and medicine · 2003 · PMID 12561044

Abstract summary (English) BACKGROUND AND OBJECTIVES: In order to optimize photorejuvenation of human skin, a method must be developed to reliably compare the potential for epidermal preservation and dermal fibroblast stimulation of different laser devices and irradiation parameters. We describe a novel human skin tissue culture model developed for this purpose. MATERIALS AND METHODS: An artificial skin model, consisting of human...

Comparative Study, Journal Article, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, Non-P.H.S., Research Support, U.S. Gov't, P.H.S.

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Suggested interpretation

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