Laser toning qswitched or picosecond evidence for PIH

Abstract summary (English) BACKGROUND: The nevus of Ota is an uncommon pigmentary skin condition that causes bluish-gray pigmentation and is traditionally treated with a Q-switched laser. Emerging evidence suggests that the 755-nanometer picosecond alexandrite laser is a safe and effective therapeutic option. We sought to determine the overall effectiveness and safety profile of the 755-nanometer (nm) picosecond alexandrite laser for managing...

Journal Article, Systematic Review, Meta-Analysis

Abstract summary (English) BACKGROUND: Understanding histologic and ultrastructural changes in pigmented lesions after laser/energy-based device (EBD) treatment is essential for elucidating treatment mechanisms, optimizing outcomes, and preventing complications. OBJECTIVE: To summarize histologic and imaging findings after laser/EBD for pigmented lesions. METHODS: A systematic review using PubMed identified 39 studies examining laser/EBD...

Systematic Review, Journal Article, Review

Abstract summary (English) INTRODUCTION: Laser treatment is one of the most common methods currently used to treat melasma. Here in, we reviewed RCTs with at least one laser therapy arm used in net form for treatment, so as to assess the use of laser therapy for melasma treatment with a degree of certainty. METHODS: A systematic literature search was performed on the effectiveness of laser therapy for melasma treatment in the period from 2010...

Journal Article, Meta-Analysis, Systematic Review

Abstract summary (English) Laser therapy plays an essential role in the management of melasma. However, direct comparisons between the fractional Q-switched ruby laser (fQSRL) and the Q-switched 1064-nm Nd: YAG laser (QSNY) are limited, particularly in Asian populations. Therefore, we conducted this study to compare the clinical efficacy, safety, and patient-reported outcomes of fQSRL versus QSNY in the treatment of melasma.

Journal Article, Randomized Controlled Trial, Comparative Study

Abstract summary (English) INTRODUCTION: Post-inflammatory hyperpigmentation is a common dermatologic complaint that affects different parts of the body. Axillary hyperpigmentation (AH) is a common dermatologic complaint, with no standard treatment. We aim to address the efficacy and safety of the studied treatment modalities for AH.

Systematic Review, Journal Article

Abstract summary (English) BACKGROUND: Skin hyperpigmentation, caused by excessive melanin production, presents both aesthetic and psychological concerns. The Q-switched Nd:YAG laser is a key treatment modality, with effectiveness influenced by factors such as skin type, laser fluence, and treatment frequency. A multimodal approach combining laser therapy and medical treatment may enhance outcomes.

Journal Article, Randomized Controlled Trial

Abstract summary (English) BACKGROUND: Solar lentigines, resulting from chronic UV exposure, are early signs of photoaging and can significantly affect individuals. AIMS: This systematic review evaluates the efficacy, safety, and tolerability of treatments for solar lentigines in light of a lack of conclusive evidence regarding optimal therapy options. METHODS: A systematic search of PubMed/Medline, EMBASE, Cochrane Library, and...

Systematic Review, Journal Article

Abstract summary (English) Melasma significantly impacts life quality, and while various laser therapies show promise, rigorous comparative studies, especially between the novel Picosecond Alexandrite Laser (PSAL) and the traditional combined modality of Q-switched and Long-pulse Nd: YAG Lasers (QLNYL), are notably lacking. This study aims to fill this gap by evaluating the efficacy and safety of these modalities, providing insights into...

Journal Article, Randomized Controlled Trial, Comparative Study

Abstract summary (English) BACKGROUND: Although post-inflammatory hyperpigmentation (PIH) is a common adverse event following laser procedures, studies evaluating its risk remain limited. OBJECTIVE: To analyze PIH risk after 532 nm Q-switched Nd:YAG laser (QSNYL) treatment for solar lentigines and examine the efficacy of triple combination cream (TCC) for its prevention. METHODS: In this single center, investigator-blinded, randomized...

Journal Article, Randomized Controlled Trial

Abstract summary (English) BACKGROUND: Melasma is a common pigmentary and photoaging disorder. Although various treatments, including 1,064-nm Q-switched neodymium-doped yttrium aluminum garnet (QS-Nd: YAG) laser toning, are available for melasma, results are often unsatisfactory. OBJECTIVE: We aimed to determine the efficacy and safety of 532-nm QS-Nd: YAG laser (shortwave toning) in patients with melasma and facial rejuvenation.

Journal Article, Randomized Controlled Trial, Comparative Study