GLASS LAB · Medical Aesthetics Evidence Index 303 cells · 19,226 papers · 5,969 top-tier evidence

Pigment · Solar lentigo / sunspot

IPL bbl photorejuvenation evidence for Solar lentigo / sunspot

B 50.0 / 100 Supported 8 RCT/meta · 5 clinical/observational · 8 case · 55 total
Good evidence · positive conclusion

There is a relatively good level of clinical evidence, and a majority of papers support its effectiveness.

Grade combines the quantity and quality of the research, while direction is a separate signal showing how the papers assess effectiveness.

Includes meta-analysis/SR Median year 2010 Last 5 years 14% Positive results 64% Negative results 1 Korea/Asia 13

Known in Korea as

IPLLPL튠라이트바디 BBL

Procedure and brand names vary, but the evidence above applies to the same procedure mechanism.

Key papers

tier1 Treatment of Solar Lentigines: A Systematic Review of Clinical Trials. Journal of cosmetic dermatology · 2025 · PMID 40145274

Abstract summary (English) BACKGROUND: Solar lentigines, resulting from chronic UV exposure, are early signs of photoaging and can significantly affect individuals. AIMS: This systematic review evaluates the efficacy, safety, and tolerability of treatments for solar lentigines in light of a lack of conclusive evidence regarding optimal therapy options. METHODS: A systematic search of PubMed/Medline, EMBASE, Cochrane Library, and...

Systematic Review, Journal Article

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tier1 Treatment of Lentigines: A Systematic Review. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2023 · PMID 36533790

Abstract summary (English) BACKGROUND: Treatments for solar lentigines include topical and physical therapies, including chemical peels, lasers, intense pulsed light, and cryotherapy. A direct comparison of treatment methods and their efficacy is lacking. OBJECTIVE: To compare treatment efficacy and adverse events for different treatment modalities for lentigines.

Systematic Review, Journal Article

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tier1 Intense Pulsed Light on skin rejuvenation: a systematic review. Archives of dermatological research · 2021 · PMID 34609598

Abstract summary (English) Aged skin is characterized by appearance of wrinkles, vascular lesions, hyperpigmentation, lentignes, texture, rhytides, and pores. These changes occur under the influence of intrinsic and extrinsic factors, as hormone alterations and exposure to ultraviolet light (UV) irradiation, respectively. Skin changes associated with aging have been assuming an important role in nowadays and bring to affect the quality of...

Journal Article, Systematic Review

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tier1 Efficacy of D-pigment dermocosmetic lightening product for solar lentigo lesions of the hand: A randomized controlled trial. PloS one · 2019 · PMID 31042723

Abstract summary (English) Solar lentigo, benign lesions which mostly appear on chronically, sun-exposed surfaces, are associated with ageing. Patients are increasingly requesting a more uniform skin texture, especially for hands. Treatment options include dermoabrasion, intense pulsed light, cryotherapy, peelings, and laser therapy.

Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't

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tier1 A split-face, evaluator-blind randomized study on the early effects of Q-switched Nd:YAG laser versus Er:YAG micropeel in light solar lentigines in Asians. Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology · 2014 · PMID 24409833

Abstract summary (English) BACKGROUND: Asians are prone to develop epidermal pigmentary lesions as a result of photoaging. Solar lentigines, especially those which are light in color, show somewhat limited response to pigment lasers and intense pulsed light sources. OBJECTIVES: We sought to compare the early effects as well as side effects of Q-switched Nd:YAG and Er:YAG micropeel in treating light solar lentigines in Asians.

Comparative Study, Journal Article, Randomized Controlled Trial

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tier1 Split-face treatment of facial dyschromia: pulsed dye laser with a compression handpiece versus intense pulsed light. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2008 · PMID 18318731

Abstract summary (English) BACKGROUND: Many visible light lasers and intense pulsed light (IPL) devices are available to treat photodamaged skin. OBJECTIVES: The objective was to perform a multiple-treatment split-face comparison evaluating a pulsed dye laser (PDL) with a compression handpiece versus IPL for photorejuvenation. METHODS: Ten subjects were treated three times at 3- to 4-week intervals.

Comparative Study, Journal Article, Randomized Controlled Trial

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tier1 A comparison of Q-switched alexandrite laser and intense pulsed light for the treatment of freckles and lentigines in Asian persons: a randomized, physician-blinded, split-face comparative trial. Journal of the American Academy of Dermatology · 2006 · PMID 16635661

Abstract summary (English) BACKGROUND: Q-switched (QS) pigmented lasers and intense pulsed light (IPL) successfully treat pigment disorders. OBJECTIVE: We sought to compare efficacy and side effects of QS alexandrite laser (QSAL) and IPL for freckle and lentigo treatment in Asians. METHODS: In all, 15 patients with freckles and 17 patients with lentigines were treated randomly with one session QSAL in one cheek and two sessions IPL in the...

Comparative Study, Journal Article, Randomized Controlled Trial

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tier1 The effect of full-face broadband light treatments alone and in combination with bilateral crow's feet Botulinum toxin type A chemodenervation. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2004 · PMID 15008861

Abstract summary (English) BACKGROUND: Broadband light (BBL; Intense Pulsed Light; Lumenis Ltd., Yokneam, Israel) is a powerful, nonablative, light-based technology that targets melanin and hemoglobin and stimulates the formation of collagen and elastin. Botulinum toxin type A (BTX-A; BOTOX; Allergan Inc., Irvine, CA) treatment of the lateral periocular region relaxes the vertical fibers of the orbicularis oculi and results in softening of...

Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial

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tier2 Efficacy and safety of intense pulsed light with a KTP filter for the treatment of solar lentigines. Lasers in surgery and medicine · 2019 · PMID 30681160

Abstract summary (English) BACKGROUND: Optical energy-based devices, including intense pulsed light (IPL) and potassium titanyl phosphate (KTP) lasers achieve reduction of pigmented and vascular lesions in a relatively similar number of treatments. This study aimed to evaluate the efficacy and safety of an IPL with a "KTP-like" filter emitting a wavelength of 525-585 nm for the treatment of solar lentigines on the hands and face. METHODS:...

Clinical Trial, Journal Article, Research Support, Non-U.S. Gov't

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tier2 Clinical evaluation of the efficacy and safety of combined bipolar radiofrequency and optical energies vs. optical energy alone for the treatment of aging hands. Lasers in medical science · 2017 · PMID 28643046

Abstract summary (English) Different treatment modalities are used for the treatment and esthetic improvement of aging hands. This study evaluated the efficacy and safety of a novel technology, which combines bipolar radio frequency (RF) and optical energies for the cosmetic treatment of aging hands. The objective of the study was to assess the efficacy, safety, tolerability, and patient satisfaction of combined bipolar radiofrequency and...

Clinical Trial, Comparative Study, Journal Article

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Suggested interpretation

Strong evidence base

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