Injectable lipolysis deoxycholate or mesotherapy evidence for Jowl fat
This is an early evidence stage based mainly on observational studies and case reports. Use it as supplementary reference, and follow your doctor's judgment for treatment decisions.
Grade combines the quantity and quality of the research, while direction is a separate signal showing how the papers assess effectiveness.
Includes meta-analysis/SR Median year 2020 Last 5 years 25% Positive results 50%
Known in Korea as
Procedure and brand names vary, but the evidence above applies to the same procedure mechanism.
Key papers
tier2 Jowl Reduction With Deoxycholic Acid.
Abstract summary (English) BACKGROUND: The study proposes a novel protocol for targeting the jowls using deoxycholic acid (DCA) injections, with emphasis on safety and feasibility of the procedure. METHODS: This prospective study was conducted at a cosmetic practice between June 2016 and May 2017. Twelve consecutive patients seeking reduction/improvement in mild/moderate jowl fat were injected with DCA subcutaneously in a predefined circular...
Clinical Trial, Journal Article
View on PubMedtier0_review Management of Serious Adverse Events Following Deoxycholic Acid Injection for Submental and Jowl Fat Reduction: A Systematic Review and Management Recommendations.
Abstract summary (English) Pivotal Phase 3 randomized control trials have demonstrated a favorable safety profile for ATX-101 in submental fat (SMF) reduction; however, in real-world settings, several serious adverse events (SAEs) have been reported, most of which are procedure related and avoidable. Current understanding of the management of uncommon AEs and SAEs is based on the aesthetic surgeon's discretion, and overzealous protocols for...
Journal Article, Review
View on PubMedtier_other Improvement in Jowl Fat following ATX-101 Treatment: Results from a Single-Site Study.
Abstract summary (English) BACKGROUND: Jowl fat overhang can reduce jawline definition. The most common treatment to reduce jowl fat is liposuction. ATX-101 (deoxycholic acid injection), a minimally invasive treatment approved for submental fat reduction, may also be an effective treatment for jowl fat.
Journal Article, Video-Audio Media
View on PubMedtier_other Novel Surface Anatomic Landmarks of the Jowl to Guide Treatment with ATX-101.
Abstract summary (English) Facial appearance is critical to physical attractiveness, and maintaining a youthful face and neck is a major motivation for individuals seeking facial cosmetic procedures. A strong mandibular border without prominent jowls is one sign of a youthful face as jowling occurs with age, contributing to squaring of the face and loss of jawline definition. Excess jowl fat has traditionally been reduced with surgical...
Journal Article
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