GLASS LAB · Medical Aesthetics Evidence Index 303 cells · 19,226 papers · 5,969 top-tier evidence

Acne / Scar / Texture · Enlarged pores

Chemical peel evidence for Enlarged pores

C 46.4 / 100 Supported 0 RCT/meta · 3 clinical/observational · 1 case · 7 total
Early-stage evidence

This is an early evidence stage based mainly on observational studies and case reports. Use it as supplementary reference, and follow your doctor's judgment for treatment decisions.

Grade combines the quantity and quality of the research, while direction is a separate signal showing how the papers assess effectiveness.

Median year 2019 Last 5 years 29% Positive results 86% Korea/Asia 1

Known in Korea as

라라필밀크필블랙필플라필각질제거 피지제거 라라필

Procedure and brand names vary, but the evidence above applies to the same procedure mechanism.

Key papers

tier2 An Advanced, Physician-Strength Retinol Peel Improves Signs of Aging and Acne Across a Range of Skin Types Including Melasma and Skin of Color. Journal of drugs in dermatology : JDD · 2019 · PMID 31524348

Abstract summary (English) Background: Facial chemical peels are highly sought after by patients with photodamage, acne, and melasma. An advanced, physician-strength superficial peel, containing 3% retinol with other firming and volumizing ingredients was developed to exfoliate, improve the appearance of fine lines and wrinkles, and plump and firm skin, while promoting a bright, even complexion. Objective: A clinical study was conducted to...

Clinical Trial, Journal Article

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tier2 A novel method to measure conspicuous facial pores using computer analysis of digital-camera-captured images: the effect of glycolic acid chemical peeling. Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2011 · PMID 21342294

Abstract summary (English) BACKGROUND/PURPOSE: Chemical peeling is becoming increasingly popular for skin rejuvenation in dermatological esthetic surgery. Conspicuous facial pores are one of the most frequently encountered skin problems in women of all ages. This study was performed to analyze the effectiveness of reducing conspicuous facial pores using glycolic acid chemical peeling (GACP) based on a novel computer analysis of...

Clinical Trial, Journal Article

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tier2 The utilization of nonthermal blue (405-425 nm) and near infrared (850-890 nm) light in aesthetic dermatology and surgery-a multicenter study. Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology · 2005 · PMID 16414904

Abstract summary (English) BACKGROUND: A major cause of skin aging is a chronic micro-inflammation triggered by UV radiation and external pollutants. It has been demonstrated that blue light diminishes inflammatory conditions and near infrared light enhances circulation. OBJECTIVES: To assess the effectiveness of a non thermal dual wavelength -- blue (405 - 420 nm) and near infrared (850 - 900 nm) -- light source in skin rejuvenation, in the...

Controlled Clinical Trial, Journal Article, Multicenter Study

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tier0_review Chemical reconstruction of skin scars (CROSS) method for atrophic scars: A comprehensive review. Journal of cosmetic dermatology · 2020 · PMID 32573079

Abstract summary (English) BACKGROUND: Chemical reconstruction of skin scars (CROSS) applies a high strength acid focally to treat atrophic scars. Although this method has gained popularity over the past two decades, no standardized treatment guideline exists for CROSS method in the treatment of atrophic scars. AIMS: The purpose of this comprehensive review was to evaluate the indications, detailed techniques, efficacy, and safety of CROSS...

Journal Article, Review

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tier3 Case Series: Therapeutic Combination of VoluDerm Radiofrequency Microneedling and Glycolic Acid Peel in Scaled-Up Concentrations. Aesthetic surgery journal. Open forum · 2024 · PMID 39670217

Abstract summary (English) BACKGROUND: Glycolic acid (GA) is an α-hydroxy peeling agent that causes controlled removal of the epidermis, with or without the dermis. Studies have shown the ability of GA to stimulate fibroblast proliferation, induce collagen synthesis, and decrease collagen degradation. The VoluDerm radiofrequency microneedling (RFMN; Pollogen, Tel Aviv, Israel) utilizes an array of microelectrodes to penetrate the epidermis...

Case Reports, Journal Article

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tier_other Assessing the Benefits of an Innovative Chemical Peel Containing Biofunctionals on Adult Acne-Prone Skin: An Exploratory Interventional Study: A Preliminary Report. Journal of cosmetic dermatology · 2026 · PMID 41784356

Abstract summary (English) BACKGROUND: Acne is the most prevalent skin disorder in the United States, affecting up to 50 million people from all age groups. Treatment options include topical and systemic therapies. Limitation in many treatment options opens avenues for alternative therapies, such as chemical peeling.

Journal Article

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tier_other The safety and efficacy of salicylic acid chemical peels in darker racial-ethnic groups. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 1999 · PMID 9935087

Abstract summary (English) BACKGROUND: There is a dearth of published data regarding chemical peels in darker racial-ethnic groups. OBJECTIVE: The purpose of the present investigation was to assess the clinical efficacy and safety of a new superficial salicylic acid peel in individuals of skin types V and VI. METHODS: Twenty-five patients were included in this pilot investigation.

Journal Article

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Suggested interpretation

Limited evidence

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