Botulinum toxin a evidence for Gummy smile

Abstract summary (English) BACKGROUND: Many popular botulinum neurotoxin treatments are off-label, yet no review has comprehensively captured their effects. This study provides a systematic review of neurotoxin's off-label aesthetic applications, focusing on muscle targets, aesthetic goals, outcomes, and patient satisfaction. METHODS: A systematic review of PubMed, MEDLINE, and Web of Science was conducted per Preferred Reporting Items for...

Journal Article, Systematic Review, Meta-Analysis, Research Support, Non-U.S. Gov't

Abstract summary (English) OBJECTIVES: To evaluate and compare the treatment of excessive gingival display (EGD) with lip repositioning surgery (LRS), with or without presurgical Botox injection, using relapse as the primary outcome. MATERIALS AND METHODS: Twenty-two periodontally healthy patients with EGD were recruited and allocated into two equal groups. The intervention group (n = 11) underwent LRS with Botox preinjection into the...

Journal Article, Randomized Controlled Trial

Abstract summary (English) INTRODUCTION: Botulinum toxin type A (BoNT/A) is an effective non-surgical method for treating gummy smile (GS). This systematic review evaluated the efficacy, duration, and safety of different BoNT/A injections. METHODS: Four electronic databases were searched for relevant literature, generating 1106 references.

Journal Article, Systematic Review

Abstract summary (English) BACKGROUND: Demand for less-invasive procedures for treating gummy smile, such as botulinum toxin A injections, has increased substantially over the years. Meanwhile, the optimal injection site for botulinum toxin A injection is debated. The authors aimed to investigate the efficacy of botulinum toxin A injection at the Yonsei point for treating gummy smile.

Randomized Controlled Trial, Journal Article, Research Support, Non-U.S. Gov't

Abstract summary (English) This study aimed to determine whether administering botulinum toxin type A (BT) prior to surgery would stabilize surgical lip repositioning. A randomized controlled parallel-group clinical trial was performed. A total of 18 participants with excessive gingival display (EGD) were divided into two groups.

Randomized Controlled Trial, Journal Article

Abstract summary (English) Gummy smile has traditionally been treated with invasive or demanding surgical and orthodontic techniques. Several studies have shown that targeted injection of the upper lip elevator muscles with botulinum toxin is an effective treatment for this condition. However, no standardized injection protocol with reproducible results has yet been published.

Systematic Review, Journal Article

Abstract summary (English) Background An aesthetic smile displays a symmetrical 2 mm or less of gingival tissue. A smile with over 3 mm of gingival display can be deemed socially unaesthetic, impacting on a patient's psychosocial status. This literature review aimed to explore the role of botulinum toxin A as a treatment modality for different types of excessive gingival display (EGD) and appropriate treatment protocols.Methods A systematic...

Journal Article, Systematic Review

Abstract summary (English) BACKGROUND: Botulinum toxin type A (BTX-A) is recent technique for the treatment of gummy smile. OBJECTIVES: The aim of this randomized controlled preliminary clinical trial was to evaluate the effects of BTX-A on excessive gingiva display (EGD) reduction, muscle activity, and patient satisfaction at 2, 8, 12, 16, 21, and 25 weeks. METHODS: Group 1 (G1) received 4 points of BTX-A application (2 U/point) for...

Journal Article, Randomized Controlled Trial

Abstract summary (English) BACKGROUND: Hyperfunction of the muscles of the upper lip is considered as the most common cause of excessive gingival display (EGD). The aim of this study was to demonstrate the effectiveness of botulinum toxin (BT) injection as a conservative treatment for EGD due to muscular hyperfunction and to compare the outcome of 2 injection methods. MATERIAL AND METHODS: This study included 40 participants who were randomly...

Journal Article, Randomized Controlled Trial

Abstract summary (English) OBJECTIVE: The aim of this systematic review is to synthesize the evidence on the effectiveness and longevity of the botulinum toxin in the treatment of individuals with excessive gingival exposure. METHODS: The search was adapted to six electronic databases and gray literature. The risk of bias was assessed using the Cochrane Risk of Bias Assessment Tool for Non-Randomized and Randomized Studies of Interventions.

Journal Article, Meta-Analysis, Systematic Review